![]() RARs are involved in various biological processes, including limb bud development, skeletal growth, and matrix homeostasis. In their unbound form, RARs repress transcription of their target genes. ![]() When bound to ligands, RARs activate transcription by binding as heterodimers to the retinoic acid response elements (RARE) found in the promoter regions of the target genes. Retinoic acid receptors (RARs) act as ligand-dependent transcriptional regulators. ![]() Full Name retinoic acid receptor gamma provided by HGNC Primary source HGNC:HGNC:9866 See related Ensembl:ENSG00000172819 MIM:180190 AllianceGenome:HGNC:9866 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo Also known as RARC NR1B3 RARgamma Summary This gene encodes a retinoic acid receptor that belongs to the nuclear hormone receptor family. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |